Aleve Naproxen and Alcohol: Effects, Risks & Interactions

This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. This medicine may cause some people to become dizzy, lightheaded, drowsy, or less alert than they are normally. Even if taken at bedtime, it may cause some people to feel drowsy or less alert on arising. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert. Before having any kind of surgery or medical tests, tell your doctor that you are taking this medicine. It may be necessary for you to stop treatment for a while, or to change to a different nonsteroidal anti-inflammatory drug before your procedure.

If you think you may have symptoms of a stomach ulcer, stop taking naproxen and contact your doctor. Your doctor may tell you not to take naproxen if you have a stomach ulcer or you have had one in the past. If you need to take naproxen but are at risk of getting a stomach ulcer, your doctor may prescribe another medicine for you to take alongside naproxen to protect your stomach.

Besides dealing with various types of pain, prostaglandins are also responsible for repairing the stomach lining. Although you can take naproxen while consuming alcohol, drinking too much can irritate and damage your stomach. Taking naproxen as directed is generally not going to pose a high health risk. However, taking naproxen more often demi lovato shows off new tattoo to celebrate sobriety than necessary, in higher doses than directed, or in combination with other NSAIDs or alcohol can greatly increase the risk of these side effects. Whilst drinking alcohol in moderation with naproxen is generally considered to be safe, as an extra precaution; users should wait 12 to 17 hours after taking Naproxen before drinking alcohol.

  1. provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products.
  2. The drug’s half-life, or how long half of a single dose stays in your system, is 12–17 hours.
  3. Inpatient treatment is the most secure level of care, as patients stay overnight and are provided with 24-hour supervision.
  4. For fever and mild to moderate pain, adults between 12 and 65 years old can take one 220 mg tablet of naproxen every 12 hours.
  5. For example, naproxen 500mg tablets are more likely to increase the risk of experiencing side effects when compared to naproxen 250mg tablets.
  6. Plus, if your hangover is accompanied by any nausea, it’s probably best to steer clear of the painkiller altogether. provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex (updated 2 Jan 2024), Cerner Multum™ (updated 16 Nov 2023), ASHP (updated 10 Jan 2024) and others. Taking more than the recommended naproxen dosage could lead to an overdose and severe side effects. Therefore, you should follow your healthcare provider’s recommended dosage. They can prescribe the lowest effective dose to treat symptoms while reducing the risk of side effects.


Some anti-inflammatory medicines, including naproxen, are thought to increase the chance of you getting an irregular heartbeat (such as atrial fibrillation or atrial flutter). In rare cases, taking anti-inflammatory medicines may increase the chances of getting heart failure. Taking NSAIDs minimizes the risk of severe side effects when taking the lowest effective dose for the shortest possible time. When taken as directed, naproxen is not generally a risky medication. But combining any medication with alcohol, including naproxen, can cause various issues and potentially lead to a dependency on alcohol. It is possible to take naproxen without harmful side effects, but misusing naproxen or mixing it with alcohol can cause damage to a person’s health.

Dangers of mixing alcohol and naproxen

It contributes to inflammation in a variety of ways, including swelling and fever. By limiting the amount of prostaglandin your body can release, Aleve can reduce these effects. According to the NHS, drinking alcohol while taking naproxen is usually fine, as long as it is done in moderation.


Even with NSAIDs like naproxen, it’s important to tell your healthcare provider about all the medications you are taking in order to be clear about any potential hazards. They can help determine whether the symptoms are related to the medication and recommend alternative treatments if necessary. It is also worth noting that the effects of alcohol and naproxen can vary depending on individual factors such as age, weight, and medical history. Therefore, it is important to consult with a healthcare provider before consuming alcohol while taking naproxen or any other medication. It is important to note that consuming large amounts of alcohol while taking naproxen can be especially dangerous for people with a history of liver or kidney disease.

Heartburn drugs and drugs that protect the stomach

Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor). This medicine may cause a delay in ovulation for women and may affect their ability to have children. If you plan to have children, talk with your doctor how to search and what to ask navigator niaaa before using this medicine. If you have problems with your kidney function, talk to your doctor about the best anti-inflammatory to take. Your doctor will have to prescribe a different medicine if your pain is related to your nerves.

What Happens If You Drink Alcohol While on Naproxen?

It is highly recommended to stick to the recommended daily alcohol intake as well as taking Naproxen exactly as prescribed by your doctor for the duration intended. It is also worth noting that the half life timeline may change based on the dose of naproxen that you have been prescribed. Before mixing the two, it is recommended to familiarise yourself with the recommended daily alcohol intake to ensure that you can stay within this threshold. Naproxen, when taken as directed by a doctor, is not a risky medication.

What Should You Do If You’ve Mixed Naproxen and Alcohol?

As with all medicines, naproxen can cause certain side effects, the risk of suffering from those side effects is increased when drinking alcohol. Naproxen has an elimination half-life of 12 to goodbye letter to addiction template download printable pdf 17 hours, which means that you are okay to drink alcohol after this window of time has passed. With or without naproxen or other medications, you should only be drinking alcohol in moderation.

For this reason, it’s important to be aware of the possible dangers of mixing alcohol and Aleve. Asthma symptoms and severe allergic reactions may occur when affected individuals take aspirin. These people should avoid naproxen and all other NSAIDs because of the risk of developing severe side effects. Naproxen may interact with several prescription and nonprescription drugs. Drinking alcohol and taking naproxen may increase the risk of gastrointestinal side effects.

The drug’s half-life, or how long half of a single dose stays in your system, is 12–17 hours. Because it takes five half-lives to clear a drug from your system entirely, naproxen can linger in your system for almost three days. If you or a loved one struggles with drug or alcohol abuse, qualified healthcare professionals can help. NSAIDs like naproxen can also increase the risk of both heart attacks and stroke. This mixture can also increase the risk of abuse, dependency, and addiction. Luckily, there is treatment available for those struggling with naproxen and alcohol abuse.

Taking an over-the-counter medication like Aleve (naproxen) is common for pain. However, just because a medication is over the counter does not mean it is free of drug interactions. Aleve and similar medications like Motrin (ibuprofen) can be dangerous to mix with alcohol.

Ask your pharmacist if you have any questions about the kind of naproxen you are using. Use naproxen exactly as directed on the label, or as prescribed by your doctor. Do not take this medicine in larger amounts or for longer than recommended.

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